330. ETHNICITY AND INFLAMMATORY RESPONSE IN GIANT CELL ARTERITIS: CHALLENGING ESTABLISHED CONCEPTS

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Giant cell arteritis: intensity of the initial systemic inflammatory response and the course of the disease.

OBJECTIVE Giant cell arteritis (GCA) has a variable course. We assessed whether intensity of initial systemic inflammatory response (ISIR) can predict the course of GCA. METHODS Charts of 130 GCA patients were reviewed. ISIR intensity at presentation was determined by 5 parameters of inflammation: sedimentation rate >100 mm/h, thrombocytosis >400,000/microl, hemoglobin <11 g/dl, leukocytosis ...

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Giant cell arteritis

Giant cell arteritis (GCA), temporal arteritis or Horton’s arteritis, is a systemic vasculitis which involves large and medium sized vessels, especially the extracranial branches of the carotid arteries, in persons usually older than 50 years. Permanent visual loss, ischaemic strokes, and thoracic and abdominal aortic aneurysms are feared complications of GCA. The treatment consists of high dos...

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Giant cell arteritis.

Permanent, severe loss of vision is a feared complication; however, it is not the sole possible devastating outcome of giant cell arteritis. Myocardial infarction, ischemic stroke and limb gangrene may also occur. Thor acic aortic aneurysms are seen over 17 times more often in patients with giant cell arteritis than in age-matched controls. The optimal work-up includes erythrocyte sedimentation...

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Giant cell arteritis.

Giant cell arteritis (GCA) is the most common vasculitis of the elderly. The diagnosis can be challenging at times because of the limitation of the American Rheumatology Association (ARA) classification criteria and the significant proportion of biopsy-negative patients with GCA. We discuss the role of advanced imaging techniques, including positron emission tomography (PET) scanning, in establ...

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Giant cell arteritis mimicking idiopathic orbital inflammatory disease.

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2017

ISSN: 1462-0324,1462-0332

DOI: 10.1093/rheumatology/kex062.332